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Introduction to meta-analysis 3: Meta-analysis of continuous outcomes

Topic category Statistical methods and meta-analysis
Date and Location
Saturday 22 October 2011 - 14:00 - 15:30
Methods Group
Methods Group: 
Statistical Methods Group
Contact person
Contact person: 
Andrew Bryant (Contact this person)
First nameLast nameAffiliation and Country
First name: 
Last name: 
Affiliation and Country: 
Newcastle University, UK
First name: 
Last name: 
Affiliation and Country: 
Oxford Brookes University, UK
Target audience
Target audience: 
review authors
Is your workshop restricted to a specific audience or open to all Colloquium participants?: 
Level of knowledge required: 
Type of workshop
Type of workshop: 
Abstract text
The Cochrane Statistics Methods Group has developed a series of workshops addressing statistical guidelines as formulated in the Cochrane Handbook for Systematic Reviews of Interventions. This workshop will provide review authors with the knowledge of issues surrounding meta-analysis of continuous outcomes.

Continuous data are commonly encountered in health care. Pooling intervention effects from continuous data presents many issues. Some of these issues will be discussed in this workshop. A brief introduction to meta-analysis of continuous outcomes will be included, consisting of: data extraction (extraction of standard deviations from standard errors, confidence intervals, test statistics, P values); and dealing with outcomes measured on different scales. More complex issues will be discussed including: options for pooling estimates of intervention effect when a mix of results from analyses using change from baseline and final values have been reported; incorporation of results from analysis of covariance and regression models; and use of the generic inverse variance. Issues will be illustrated by examples. Time will be allowed for discussion of the issues raised.